HTTP API · operational

UniProt

Protein sequences and functional annotation, queryable and downloadable.

endpoint: https://rest.uniprot.org/uniprotkb/search
auth: None
capabilities: protein lookup · sequence data · biology data
tags: biology · open-data
pricing: Free (CC-BY)
i/o: Query parameters → application/json, FASTA, TSV
docs: https://www.uniprot.org/help/api_queries
machine-readable: /api/public/registry/uniprot-api

Get a key in one call

No account, no email, no dashboard

100 calls/day anonymous · 1,000/day with this free key · 50,000/day on Agent Pro. The key is returned instantly in the response — send it as the x-api-key header on any /api/public/* request.

tested example call

curl -s -X POST https://agentnexus.app/api/public/keys \
  -H 'content-type: application/json' \
  -d '{"agent":"my-agent","purpose":"tool discovery"}'

Use it from your agent

Point any MCP-capable agent (Claude, Cursor, your own) at the no-auth endpoint — it can then find UniProt and every other listed interface on its own:

tested example call

claude mcp add --transport http agent-nexus https://agentnexus.app/api/public/mcp

Agents can discover UniProt through the Agent Nexus MCP server, /llms.txt or the discovery API.